Description

1) To conduct a case-control study, you need to define the cases. Defining cases includes both a medical definition of “case” as well as an indication of where you would recruit study participants and how you confirm they are a case. Please describe these steps for a Zombie Case-Control study:

2) What information would you collect on each study participant to address potential risk factors for the disease?

3 Your study yields the following Odds Ratios. Define Odds Ratio and explain which risk factor is likely related to becoming a Zombie. Is there a risk factor which may be protective of being “turned?”

Note: Zombies are known to haunt the stacks – how does this impact your interpretation of the relative risk of studying in the stacks versus zombie contact?

Risk Factor

Odds Ratio

P

Value

Eating at the HUB

0.99

0.891

Studying in the stacks

3.0

0.030

Zombie Contact

12.0

0.001

Trilogy Coffee

0.40

0.023

4) To conduct a Cohort Study you need to define a healthy population (i.e. before they became zombies)(Hint: you can start a cohort study in the past as long as you have records to define the population).

Define the cohort you would study below, including a start date. What records on campus could be consulted to provide a list of the cohort?

5) What exposures or risk factors would you study? How would you gather data (records? interviews; other sources)? Would you collect any blood samples?

{Hint: look at the results of the case-control study. Also were other risk factors identified in initial description of the Zombie scenario?)

6) Your study yields the following results. Define Relative Risk and interpret the findings explaining what you would report back to the Medical clinic regarding how the virus spreads. Note: Zombies are known to haunt the stacks – how does this impact your interpretation of the relative risk of studying in the stacks versus zombie contact?

Risk Factor

Metric

Relative Risk

P

Value

Study in the Stacks

Yes / no

1.5

0.040

Zombie Contact

Yes / no

4.5

0.005

Eating at the CUB*

Breakfast Only

0.75

0.049

Lunch Only

1.03

0.456

All Meals

0.95

0.652

*The CUB is now serving Trilogy Coffee

7) The third type of Epidemiologic study is a Prevention Study. Do your data suggest any potential preventative strategy. Does anything seem to prevent being turned by a Zombie? How could you test this?